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I just had a thought, and I'd like to share it. I wasn't sure wether this should go here or in the other drugs section but if it's in the wrong place a mod can move it.

I've just started medication for severe migraines caused by anxiety disorder. I'm taking Metoclopramide-HCL (http://en.wikipedia.org/wiki/Metoclopramide). It helps with stress, nausia, and severe migraines. As well as being a migraine medication, it's a dopamine receptor antagonist, which is a pharmacologic agent that binds to, and blocks, the action of dopamine receptors. This essentially hinders receptor activity by preventing stimulation by dopamine. Now, dopamine is a reward chemical released by the brain. It's released naturally in different situations, but the interesting part is this. When you're addicted to something, i.e. cigarettes, dopamine is released as a reward when you take part in the addictive activity. Your brain rewards you for smoking a cigarette.

My theory is that, in low doses, this could be a very good quit-smoking aid. I've been meaning to quit smoking for a long time now and I've tried twice and failed miserably. I think I'm going to give it a shot while I'm on these little pills. I'll update every once in a while to tell you all wether it makes a difference or not. If it works I'm going to write in to the Canadian Medical Journal and let them know about this little experiment of mine. Wish me luck, guys!

well ur science is spot on there, and ur theory is sound (the science geek in me is bursting out now haha)
sounds like it would work, or at least aid in the quiting process, and from what u've sed, should work, at least a little
or it wud just make u want a smoke even more because ur not gettin the 'reward' from ur fags anymore? anyway keep us posted how it goes
and good luck

certified-nutter wrote:because ur not gettin the 'reward' from ur fags anymore?

hahahha, its funny the meaning of fags in the US and in other places mean something completely different.

SpRi7e wrote:

certified-nutter wrote:because ur not gettin the 'reward' from ur fags anymore?

hahahha, its funny the meaning of fags in the US and in other places mean something completely different.

Hahah I laughed when I read that too

edit: in US one would say "Hey, that dude in Rory's avatar is a fag crackhead"

In UK they'd be all "That crackhead un Rory's avatar is smoking a fag"

fags is also a not-very-often used word for gays, around here, but i dont really can gay people anything, cos they not really any different

Except when they hit on straight dudes without clarifying wether we are straight or gay.

Or when they walk around talking like fucking morons and have a limp wrist.

To me there are gay people, and there are fucking faggots. Two comepletely different types of people.

lol fags....anyways

Sounds good Rory. Keep us up to date on how it goes. Sounds like it could really work. But is it just the dopamine that makes cigs so addictive or is it more the nicotine. Because if its the nicotine that makes it so addictive over the dopamine. Then would you supplying just the dopamine make the cravings subside ?

Not trying to put holes in your theory, just speaking out loud and hopefully helping you refine your experiment because this may lead to a answer to help stop smoking. cause i really hate cigs

Or when there walking like they just rode a horse for hours....


when they're in the city.

Ziggy wrote:Sounds good Rory. Keep us up to date on how it goes. Sounds like it could really work. But is it just the dopamine that makes cigs so addictive or is it more the nicotine. Because if its the nicotine that makes it so addictive over the dopamine. Then would you supplying just the dopamine make the cravings subside ?

Not trying to put holes in your theory, just speaking out loud and hopefully helping you refine your experiment because this may lead to a answer to help stop smoking. cause i really hate cigs

I think it's the nicotine that makes them addictive. Also, didn't know that I wasn't the only person from mississauga on this site.

to fully quit cigs i think is a very big deal, thankfully i've never had that addiction...I hope everything goes well with it! keep us updated =)

its all mental.. all you have to do is fucking stop haha, i figured that out when i did acid for the first time, everythings mental and my friend quit immediately after..